Naturally repairing or reversing damage caused by degenerative disease

Frequency is pioneering a new class of small-molecule therapeutics to selectively activate progenitor cells already present within the body to create healthy functional tissues and organs.

Sensorineural Hearing Loss (SNHL)

Discovery
Preclinical
Phase 1
Phase 2
Phase 3
FX-322 Phase 2a – 202 Study
Phase 2

Study of noise induced and sudden SNHL patients with mild to moderately severe acquired SNHL, ages 18 – 65

Study enrolled with 95 subjects, completed June 2021

Discovery
Preclinical
Phase 1
Phase 2
Phase 3
FX-322 Phase 1b – 111 Study
Phase 1

Open-label safety study focused on administration conditions for FX-322. Subjects had mild to severe SNHL, ages 18 – 65

Study enrolled with 33 subjects, completed March 2021

Discovery
Preclinical
Phase 1
Phase 2
Phase 3
FX-322 Phase 1b – 112 Study
Phase 1

Study of mild to moderately severe age-related hearing loss patients, ages 66 – 85

Study enrolled with 30 subjects, completed May 2021

Discovery
Preclinical
Phase 1
Phase 2
Phase 3
FX-322 Phase 1b – 113 Study
Phase 1

Study of patients with severe SNHL, ages 18 – 65

Study enrolled with 31 subjects, read out planned for H2 2021

Multiple Sclerosis

DISCOVERY
PRECLINICAL
PHASE 1
PHASE 2
PHASE 3
Remyelination in Multiple Sclerosis
Preclinical

Clinical Trials Information

For more information on the phase 2a clinical trial for FX-322, please visit clinicaltrials.gov.

Expanded Access Policy

Learn about our expanded access policy.

Our Program for Sensorineural Hearing Loss

Advancing FX-322 into a Phase 2a clinical study for the most common form of hearing loss

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Our Program for Multiple Sclerosis

Discovery science focused on activating progenitor cells in the central nervous system to repair myelin

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