Inspired by the real-world impact of the most common form of hearing loss.

Pioneering an approach to therapies that may have applications for a broad range of degenerative disease, beginning with sensorineural hearing loss and multiple sclerosis

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Reimagining Treatments for Hearing Loss

More than 40 million people in the U.S. struggle with sensorineural hearing loss, the most common type of hearing loss. This condition affects more than just hearing; it’s about understanding, confidence, and connection. Individuals may have difficulty speaking on the phone, struggle in certain jobs, and become socially isolated. What may start as a minor inconvenience can get progressively worse.

Untreated, individuals face associated risk of depression and dementia. Current treatments can help make sounds louder, but we’re leading the creation of the first-ever disease-modifying therapy for sensorineural hearing loss — one that aims to restore hearing function and enhance the ability to clearly understand speech.

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Building a Novel Regenerative Medicine Platform

We are pioneers of Progenitor Cell Activation (PCA). Similar to stem cells, progenitor cells are pre-programmed to create specific cell types. In the inner ear, for example, they generate the sensory hair cells that enable us to hear.

We believe this approach can be applied to a range of tissues and organs affected by degenerative disease. We’re creating a new class of therapeutics that aims to activate these progenitor cells using small molecules that do not alter genes and which can be delivered with less complexity than current regenerative medicines.

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Understanding Speech Intelligibility

News & Insights


August 25, 2020

Watch an HLAA panel discussion on the potential of regenerative medicines to restore hearing loss

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April 13, 2021

Frequency Therapeutics Expands its Clinical Development Team, Adding Expertise in Inner Ear Physiology and Translational Science

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April 9, 2021

Frequency Therapeutics to Present at the 20th Annual Needham Virtual Healthcare Conference

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Join Our Team

Learn more about Frequency, our team and culture, and opportunities to grow your career.

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