Activating cells within the body to restore or repair the underlying causes of hearing loss and multiple sclerosis

We are a clinical-stage biotechnology company focused on restoring function – first in hearing loss and then in multiple sclerosis – by developing therapeutics that activate a person’s innate regenerative potential within the body.

Our proprietary approach, progenitor cell activation (PCA), uses small molecules to activate progenitor cells within the body to create functional tissue.

Our initial therapeutic focus is sensorineural hearing loss (SNHL), which accounts for 90 percent of all hearing loss. SNHL is typically caused by the permanent loss of sensory hair cells in the cochlea within the ear. FX-322, our lead product candidate, is designed to regenerate hair cells through the activation of progenitor cells already present in the cochlea.

Applying the same underlying science and approach we use to regenerate sensory hair cells in the inner ear, Frequency also seeks to activate existing progenitor cells in patients with multiple sclerosis to remyelinate axons and restore signal transmission. Our scientists are following early restorative signals in preclinical studies.

Our approach aims to reduce the complexity of regenerative medicine

We use small molecules to activate progenitor cells and other precursor cells where they are located, bypassing many of the challenges of cell and gene therapies.

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Focused on repairing the underlying cause of sensorineural hearing loss

In hearing we are working to regenerate hair cells through the activation of progenitor cells already present in the cochlea.

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